GESV pipeline

The GESV (Genome-edited Sequence Variants) pipeline assembles sequence variants (SVs) from amplicon data and compares them to a reference sequence to identify edit types and frequencies. By condensing raw amplicon data into distinct SVs while preserving their abundance information, GESV significantly streamlines amplicon sequencing–based genotyping of gene-edited organisms.

logo

Schematic workflow of GESV analysis

Run GESV pipeline

To run the GESV analysis online, please provide sample information and upload the ZIP file containing raw FASTQ data.

Download offline gui apllication to run GESV pipeline locally, GESV-local .

More information about GESV pipeline can be found in the Hu_et_al_GESV_2025 GitHub repository.

SampleID GeneID Ref_sequence R1 Primer R2 Primer Details Action
Default: 50. SVs with abundance >= threshold and >=12 consecutive matches will be classified as 'High confidence'